Misoprostol is a synthetic prostaglandin that works by replacing prostaglandins whose production is blocked by aspirin or NSAIDs. It is used to prevent stomach ulcers from developing during treatment with aspirin or an NSAID. Misoprostol is a synthetic prostaglandin E 1 analogue marketed as an oral preparation used to prevent and treat gastroduodenal damage induced by nonsteroidal anti-inflammatory drugs (NSAIDs). Find patient medical information for Misoprostol (Cytotec) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Misoprostol is used to prevent ulcers in people who take certain arthritis or pain medicines, including aspirin, that can cause ulcers. It protects the stomach lining and decreases stomach acid secretion. Misoprostol is used to decrease the risk of having stomach ulcers in patients taking nonsteroidal anti-inflammatory drugs (NSAIDs) including aspirin. This medicine works by helping the stomach protect itself against acid damage, and decreases the amount of acid produced by the stomach. Includes Misoprostol indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more. Misoprostol is a very powerful stimulator of uterine contractions in late pregnancy and can cause fetal death and uterine rupture if used in high doses. Follow the dosage regimes carefully and do not exceed those doses. Misoprostol by mouth is the least effective treatment for producing complete abortion in a period of 24 hours due to the liver's first-pass effect which reduces the bioavailability of the misoprostol. There are currently multiple dedicated Misoprostol products on the global medication market. A list and detailed map can be accessed by clicking the link below. Learn how to safely use misoprostol for an abortion, including dosage, protocol, expected symptoms, side effects, and precautions. Get detailed guidance for a safe abortion process.